Unusual or atypical wounds are those that are uncommon, and do not follow the usual healing pattern. These wounds arise from uncommon aetiologies such as infection, metabolic and genetic disorders, inflammatory processes and external or traumatic causes.

Examples of such wounds are:

  • Infection: Necrotising fasciitis, atypical mycobacteria, deep fungal infections
  • Metabolic and genetic disorders: Calciphylaxis, Sickle cell anaemia
  • Inflammatory causes: Vasculitis, Pyoderma gangrenosum,
  • Dermatological Conditions: Bullous pemphigoid, Epidermolysis bullosa
  • External or traumatic causes: burns, bites and stings, radiation, necrosis

Necrotising Fasciitis

Necrotizing Fasciitis is a serious bacterial infection that spreads rapidly and destroys the body’s soft tissue. Commonly called a “flesh-eating disease” by the media, this infective process is often polymicrobial with the most common causative bacteria being: group A Streptococcus , Klebsiella, Clostridium, Escherichia coli, Staphylococcus aureus, Vibrio vulnificus, and Aeromonas hydrophila, among others. Accurate diagnosis and prompt treatment with antibiotics is essential.

Pyoderma Gangrenosum

Pyoderma gangrenosum (PG) is a condition that causes tissue to become necrotic, causing ulcers that commonly occur on the legs, buttocks and abdomen. When they occur, they can lead to chronic wounds. PG can initially look like small bug bites or pimples, and may progress to larger ulcers. Though the wounds rarely lead to death, they can cause pain and scarring.


Vasculitis is an inflammation of the blood vessels in the body. Vasculitis occurs when the body’s immune system targets and damages the blood vessels. Vasculitis is the underlying cause of some leg ulcers.